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Complications

Infections

In some lymphatic conditions, abnormal lymphatic vessels and fluid buildup can increase the risk of infection and inflammation. The lymphatic system plays an important role in immune function, so when the lymphatic system does not work as it should, the body may have a harder time fighting infection.

Not everyone with a lymphatic condition experiences infections, and severity can vary widely.


Why Infection Can Occur

Several factors may increase risk, including:

  • Slowed or blocked lymphatic flow, which can limit immune cell movement
  • Fluid buildup, which can create an environment where infection is more likely
  • Skin changes or leakage of lymphatic fluid, which can allow bacteria to enter
  • Some patients with complex lymphatic malformation may have reduced numbers of infection fighting cells

These factors can make some areas of the body more vulnerable.


Possible Signs and Symptoms

Symptoms may be mild or more noticeable and can include:

  • Redness, warmth
  • Pain or tenderness
  • Fever or chills
  • Increased swelling or tightness

Some people experience recurrent episodes, while others may only have a single infection.


How Infections Are Evaluated

Evaluation depends on symptoms and location and may include:

  • Physical examination
  • Blood tests if infection is suspected
  • Imaging to look for fluid buildup or tissue changes

Prompt evaluation helps determine whether symptoms are due to infection, inflammation, or another cause.


Management and Prevention

Management depends on the cause and severity. Some people benefit from:

  • Early treatment of infections
  • Monitoring areas prone to swelling or skin changes
  • Ongoing care with providers familiar with lymphatic conditions

Care plans are individualized and may change over time.

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