2025
Efficacy and Safety of Trametinib Therapy for Complex Lymphatic Malformations.
Xu Y, Zhou J, Lan Y, Ji Y.
PMID: 41116710
Complex Lymphatic Anomalies: A Comprehensive Review of Imaging Features and Diagnostic Considerations.
Pratt M, Dillenbeck J, Pimpalwar S, Yang J, Sibley RC.
PMID: 41349185
Targeted Medical Therapies for Vascular Anomalies: A Clinical Review.
Eng W.
PMID: 41307267
First successful case of in-utero medical management of fetal cervical lymphatic malformation using sirolimus in Singapore.
Bhatia A, Thain SP, Tan LK, Chan MY, Tan JVK.
PMID: 41321099
Qualitative Assessment of the Patient-Reported Outcome Measure for Vascular Malformation (PROVAM) Questionnaire in Patients with Low-Flow Vascular Malformations: A Prospective Cohort Study.
Garg T, Choi R, Ring NY, England RW, Gong AJ, Weiss CR.
PMID: 41094085
Rescue of Angiopoietin-2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells.
Sun RW, Zhang H, Mehdi SJ, Bowen JK, Burnett AK, Richter GT, Washam CL, Byrum SD, Wu JK, Shawber CJ, Strub GM.
PMID: 41399917
Multidimensional single-cell analysis reveals immune dysfunction and inflammatory response in Lymphatic malformations.
Chen C, Ju W, Li X, Yao K, Cao J, Duan S, Lv X, Zhang T, Li S, Li J, He F, Sun B, Shen G.
PMID: 41273773
High depth targeted next-generation sequencing in vascular malformations.
Pakhathirathien P, Wongkittichote P, Wittayakornrerk S, Treesit T, Feinggumloon S, Pichipichatkul K, Bua-Ngam C, Sarovath A, Thanachatchairattana P, Dumrongwongsiri S, Bowling KM, Corliss MM, Cao Y, Tim-Aroon T, Khongkraparn A, Noojaroen S, Wattanasirichaigoon D.
PMID: 41224725
VA-Comm: Developing and Piloting a Novel Communication Tool for Complex Lymphatic Anomalies and Lymphatic Malformations.
Sisk BA, Kepper MM, Bereitschaft C, Milam S, Chen S, Nakano TA, Wu MD, Borst AJ, Kerr AM.
PMID: 41185141
A high-throughput zebrafish screen identifies novel candidate treatments for kaposiform lymphangiomatosis (KLA).
Bassi I, Jabali A, Levin L, Lambiase G, Moshe N, Farag N, Tevet Y, Perlmoter G, Egozi S, Leichner GS, Geva P, Barzilai A, Avivi C, Long J, Otterstrom JJ, Paran Y, Barr H, Yaniv K, Greenberger S.
PMID: 40838953
Expansion of the Phenotype of Lymphatic Anomalies Caused by Somatic Activating BRAF Variant.
Fox MD, Kumar S, Britt AD, Srinivasan AS, Surrey LF, Vatsky SE, Borst AJ, Hakonarson H, Li D, Sheppard SE, Snyder KM, Adams DM.
PMID: 40884273
Human Lymphatic Endothelial Cells Expressing NRAS(Q61R) Model Characteristics of Kaposiform Lymphangiomatosis.
Fox DA, McDaniel CG, Pastura P, Le Cras TD.
PMID: 40879319
Molecular targeted treatment in infants with central conducting lymphatic anomalies.
van den Brink VC, Kleimeier LER, Leenders EKSM, Klein WM, de Boode WP, Fuijkschot J, Vrancken SLAG.
PMID: 40835771
Oncogenic GOPC-ROS1 fusion promotes the formation of lymphatic malformations by impairing tight junction and its crizotinib resistance through repressing ferroptosis.
Tian R, Weng Z, Liang H, Zhang C, He Q, Li J, Zhang R, Yin X, Deng D, Hong L, Gu S, Zhan Z.
PMID: 40819798
RAS Pathway Mutations and Therapeutics in Vascular Anomalies.
Alharbi S, Merkle S, Hammill AM, Waters AM, Le Cras TD.
PMID: 39984187
Semaphorin 3A and 3F Promote Lumen Expansion in TIE2-Mutated Venous Malformation.
Schrenk S, Sherpa C, Bischoff LJ, Cai Y, Boscolo E.
PMID: 41127911
Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling.
Bischoff LJ, Schrenk S, Soroko K, Sherpa C, Arasu A, Reynaud D, Boscolo E.
PMID: 41074681
Angiopoietin-TIE2 feedforward circuit promotes PIK3CA-driven venous malformations.
Kraft M, Schoofs H, Petkova M, Andrade J, Grosso AR, Benedito R, De Roo AK, Boon LM, Vikkula M, Kapp FG, Hägerling R, Potente M, Mäkinen T.
PMID: 40410415
