In this compelling presentation, Dr. Kathleen Cullion MD, PhD, Assistant Director of the Kohane Laboratory of Biomaterials and Drug Delivery at Boston Children’s Hospital, details her team’s novel approach to treating venous malformations using nanomedicine. Drawing on years of research and collaboration, she outlines the development of nanoparticle drug delivery systems and photothermal therapy to improve treatment precision while minimizing side effects.
Dr. Cullion explains how venous malformations (VMs)—debilitating vascular anomalies often resistant to traditional therapies—can be targeted using nanoparticles engineered for enhanced permeability and retention (EPR). She also discusses the potential for light-activated delivery and photothermal ablation to safely and effectively regress VMs in preclinical models.
From identifying molecular pathways like TIE2/PI3K to designing targeted gold nanoshells, this talk provides an exciting glimpse into the future of vascular anomaly treatment. Watch to learn how these advances could transform care for patients living with complex vascular diseases.
- Learn more about nanomedicine applications in rare diseases
- Hear about promising new strategies for deeper, safer targeting
- Explore what’s next in personalized vascular anomaly therapy
